UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

SCHEDULE 13G*

(Rule 13d-102)

 

INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT

TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED

PURSUANT TO § 240.13d-2

(Amendment No. __)*

 

OnKure Therapeutics, Inc.
(Name of Issuer)
 
Class A Common Stock, par value $0.0001 per share (the “Shares”)
(Title of Class of Securities)
 
68277Q105
(CUSIP Number)
 
October 4, 2024
(Date of Event Which Requires Filing of the Statement)

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

 

¨ Rule 13d-1(b)
x Rule 13d-1(c)
¨ Rule 13d-1(d)

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

 

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

 

 

CUSIP NO. 68277Q105 13G Page 2 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Citadel Advisors LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

1,262,177 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

9.8%1

12.

TYPE OF REPORTING PERSON

 

IA; OO; HC

 

 

1 The percentages reported in this Schedule 13G are based upon approximately 12,852,152 Shares outstanding comprised of (i) approximately 12,652,811 Shares outstanding as of October 4, 2024 (according to the issuer’s Current Report on Form 8-K as filed with the Securities and Exchange Commission on October 8, 2024), and (ii) approximately 199,341 Shares issuable upon conversion of certain shares of non-voting common stock held by affiliates of the Reporting Persons. In accordance with the issuer’s Amended and Restated Certificate of Incorporation, in no event shall the holder of shares of such class of non-voting common stock be entitled to convert such shares of non-voting common stock for any number of Shares that, upon giving effect to such exercise, would cause the aggregate number of Shares owned by the Reporting Persons to exceed 9.9% of the Shares outstanding immediately after giving effect to such conversion. Except as described in the preceding sentence, all Shares for the holdings of the reporting persons reported in this Schedule 13G are as of the opening of the market on October 11, 2024.

 

 

 

 

CUSIP NO. 68277Q105 13G Page 3 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Citadel Advisors Holdings LP

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

1,262,177 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

9.8%

12.

TYPE OF REPORTING PERSON

 

PN; HC

 

 

 

 

CUSIP No. 68277Q105 13G Page 4 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Citadel GP LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

1,262,177 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

9.8%

12.

TYPE OF REPORTING PERSON

 

OO; HC

 

 

 

 

CUSIP No. 68277Q105 13G Page 5 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Citadel Securities LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

9,194 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

0.1%

12.

TYPE OF REPORTING PERSON

 

BD; OO

 

 

 

 

CUSIP No. 68277Q105 13G Page 6 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Citadel Securities Group LP

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

9,194 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

0.1%

12.

TYPE OF REPORTING PERSON

 

PN; HC

 

 

 

 

CUSIP No. 68277Q105 13G Page 7 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Citadel Securities GP LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

9,194 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

0.1%

12.

TYPE OF REPORTING PERSON

 

OO; HC

 

 

 

 

CUSIP No. 68277Q105 13G Page 8 of 13 Pages

 

1.

NAME OF REPORTING PERSONS

 

Kenneth Griffin

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

(a)     ¨

(b)     ¨

3.

SEC USE ONLY

 

4.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

U.S. Citizen

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
5.

SOLE VOTING POWER

 

0

6.

SHARED VOTING POWER

 

1,271,371 Shares

7.

SOLE DISPOSITIVE POWER

 

0

8.

SHARED DISPOSITIVE POWER

 

See Row 6 above

9.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

See Row 6 above

10.

CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

¨

11.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

 

9.9%

12.

TYPE OF REPORTING PERSON

 

IN; HC

 

 

 

 

CUSIP No. 68277Q105 13G Page 9 of 13 Pages

 

Item 1(a). Name of Issuer:
   
  OnKure Therapeutics, Inc.
   
Item 1(b). Address of Issuer’s Principal Executive Offices:
   
  18575 Jamboree Road, Suite 275-S, Irvine, CA 92612
   
Item 2(a). Name of Person Filing:
   
  This Schedule 13G is being jointly filed by Citadel Advisors LLC (“Citadel Advisors”), Citadel Advisors Holdings LP (“CAH”), Citadel GP LLC (“CGP”), Citadel Securities LLC (“Citadel Securities”), Citadel Securities Group LP (“CALC4”), Citadel Securities GP LLC (“CSGP”) and Mr. Kenneth Griffin (collectively with Citadel Advisors, CAH, CGP, Citadel Securities, CALC4 and CSGP, the “Reporting Persons”) with respect to the Shares of the above-named issuer owned by Citadel Multi-Strategy Equities Master Fund Ltd., a Cayman Islands company (“CM”), Citadel CEMF Investments Ltd., a Cayman Islands limited company (“CCIL”), and Citadel Securities.  Such owned Shares may include other instruments exercisable for or convertible into Shares.
   
  Citadel Advisors is the portfolio manager for CM and CCIL. CAH is the sole member of Citadel Advisors. CGP is the general partner of CAH. CALC4 is the non-member manager of Citadel Securities. CSGP is the general partner of CALC4. Mr. Griffin is the President and Chief Executive Officer of CGP, and owns a controlling interest in CGP and CSGP.
   
  The filing of this statement shall not be construed as an admission that any of the Reporting Persons is the beneficial owner of any securities covered by the statement other than the securities actually owned by such person (if any).
   
Item 2(b). Address or Principal Business Office or, if none, Residence:
   
  The address of each of the Reporting Persons is Southeast Financial Center, 200 S. Biscayne Blvd., Suite 3300, Miami, Florida 33131.
   
Item 2(c). Citizenship:
   
  Each of Citadel Advisors, CGP, Citadel Securities and CSGP is organized as a limited liability company under the laws of the State of Delaware. Each of CALC4 and CAH is organized as a limited partnership under the laws of the State of Delaware. Mr. Griffin is a U.S. citizen.
   
Item 2(d). Title of Class of Securities:
   
  Class A Common Stock, par value $0.0001 per share
   
Item 2(e). CUSIP Number:
   
  68277Q105

 

 

 

 

CUSIP No. 68277Q105 13G Page 10 of 13 Pages

 

Item 3. If this statement is filed pursuant to §§ 240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:
   
  (a) ¨ Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o);
  (b) ¨ Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c);
  (c) ¨ Insurance company as defined in Section 3(a)(19) of the Act (15 U.S.C. 78c);
  (d) ¨ Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
  (e) ¨ An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
  (f) ¨ An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
  (g) ¨ A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
  (h) ¨ A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
  (i) ¨ A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act (15 U.S.C. 80a-3);
  (j) ¨ A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J);
  (k) ¨ Group, in accordance with § 240.13d-1(b)(1)(ii)(K).
         
  If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:                          .
         
Item 4. Ownership:
         
  A. Citadel Advisors LLC, Citadel Advisors Holdings LP and Citadel GP LLC
         
    (a) Each of Citadel Advisors LLC, Citadel Advisors Holdings LP and Citadel GP LLC may be deemed to beneficially own 1,262,177 Shares.
         
    (b) The number of Shares that each of Citadel Advisors LLC, Citadel Advisors Holdings LP and Citadel GP LLC may be deemed to beneficially own constitutes 9.8% of the Shares outstanding.
         
    (c) Number of Shares as to which such person has:
         
      (i) sole power to vote or to direct the vote:  0
         
      (ii) shared power to vote or to direct the vote:  1,262,177
         
      (iii) sole power to dispose or to direct the disposition of:  0
         
      (iv) shared power to dispose or to direct the disposition of:  1,262,177

 

 

 

 

CUSIP NO. 68277Q105 13G Page 11 of 13 Pages

 

  B. Citadel Securities LLC
         
    (a) Citadel Securities LLC may be deemed to beneficially own 9,194 Shares.
       
    (b) The number of Shares that Citadel Securities LLC may be deemed to beneficially own constitutes 0.1% of the Shares outstanding.
       
    (c) Number of Shares as to which such person has:
       
      (i) sole power to vote or to direct the vote:  0
         
      (ii) shared power to vote or to direct the vote:  9,194
         
      (iii) sole power to dispose or to direct the disposition of:  0
         
      (iv) shared power to dispose or to direct the disposition of:  9,194
         
  C. Citadel Securities Group LP and Citadel Securities GP LLC
         
    (a) Each of Citadel Securities Group LP and Citadel Securities GP LLC may be deemed to beneficially own 9,194 Shares.
       
    (b) The number of Shares that each of Citadel Securities Group LP and Citadel Securities GP LLC may be deemed to beneficially own constitutes 0.1% of the Shares outstanding.
       
    (c) Number of Shares as to which such person has:
       
      (i) sole power to vote or to direct the vote:  0
         
      (ii) shared power to vote or to direct the vote:  9,194
         
      (iii) sole power to dispose or to direct the disposition of:  0
         
      (iv) shared power to dispose or to direct the disposition of:  9,194
         

  

 

 

 

CUSIP No. 68277Q105 13G Page 12 of 13 Pages

 

  D. Kenneth Griffin
         
    (a) Mr. Griffin may be deemed to beneficially own 1,271,371 Shares.
       
    (b) The number of Shares that Mr. Griffin may be deemed to beneficially own constitutes 9.9% of the Shares outstanding.
       
    (c) Number of Shares as to which such person has:
       
      (i) sole power to vote or to direct the vote:  0
         
      (ii) shared power to vote or to direct the vote:  1,271,371
         
      (iii) sole power to dispose or to direct the disposition of:  0
         
      (iv) shared power to dispose or to direct the disposition of:  1,271,371

  

Item 5. Ownership of Five Percent or Less of a Class:
   
  If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following. ¨
   
Item 6. Ownership of More Than Five Percent on Behalf of Another Person:
   
  Not Applicable
   
Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company:
   
  Not Applicable
   
Item 8. Identification and Classification of Members of the Group:
   
  Not Applicable
   
Item 9. Notice of Dissolution of Group:
   
  Not Applicable
   
Item 10. Certifications:
   
  By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

 

 

 

 

CUSIP No. 68277Q105 13G Page 13 of 13 Pages

 

SIGNATURE

 

After reasonable inquiry and to the best of its knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

 

Dated October 11, 2024.

 

CITADEL SECURITIES LLC   CITADEL ADVISORS LLC
         
By: /s/ Guy Miller   By: /s/ Seth Levy
  Guy Miller, Authorized Signatory     Seth Levy, Authorized Signatory
         
CITADEL SECURITIES GROUP LP   CITADEL ADVISORS HOLDINGS LP
         
By: /s/ Guy Miller   By: /s/ Seth Levy
  Guy Miller, Authorized Signatory     Seth Levy, Authorized Signatory
         
CITADEL SECURITIES GP LLC   CITADEL GP LLC
         
By: /s/ Guy Miller   By: /s/ Seth Levy
  Guy Miller, Authorized Signatory     Seth Levy, Authorized Signatory
         
      KENNETH GRIFFIN
         
      By: /s/ Seth Levy
        Seth Levy, attorney-in-fact*

 

 

*Seth Levy is signing on behalf of Kenneth Griffin as attorney-in-fact pursuant to a power of attorney previously filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of attorney was filed as an attachment to a filing by Citadel Advisors LLC on Schedule 13G for Allakos Inc. on October 13, 2023.

 

 

 

 

EXHIBIT 99.1

 

JOINT FILING AGREEMENT

 

The undersigned hereby agree that the Statement on Schedule 13G filed herewith (and any amendments thereto), relating to the Shares of OnKure Therapeutics, Inc., a Delaware corporation, is being filed jointly with the Securities and Exchange Commission pursuant to Rule 13d-1(c) under the Securities Exchange Act of 1934, as amended, on behalf of each of the undersigned.

 

This Agreement may be executed in counterparts and each of such counterparts taken together shall constitute one and the same instrument.

 

Dated October 11, 2024.

 

CITADEL SECURITIES LLC   CITADEL ADVISORS LLC
         
By: /s/ Guy Miller   By: /s/ Seth Levy
  Guy Miller, Authorized Signatory     Seth Levy, Authorized Signatory
         
CITADEL SECURITIES GROUP LP   CITADEL ADVISORS HOLDINGS LP
         
By: /s/ Guy Miller   By: /s/ Seth Levy
  Guy Miller, Authorized Signatory     Seth Levy, Authorized Signatory
         
CITADEL SECURITIES GP LLC   CITADEL GP LLC
         
By: /s/ Guy Miller   By: /s/ Seth Levy
  Guy Miller, Authorized Signatory     Seth Levy, Authorized Signatory
         
      KENNETH GRIFFIN
         
      By: /s/ Seth Levy
        Seth Levy, attorney-in-fact*

 

 

*Seth Levy is signing on behalf of Kenneth Griffin as attorney-in-fact pursuant to a power of attorney previously filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of attorney was filed as an attachment to a filing by Citadel Advisors LLC on Schedule 13G for Allakos Inc. on October 13, 2023.